Kogure et al. [63] performed exosomal miRNA profiling in donor HCC cells in vitro and identified that miRNAs contained within exosomes modulate gene expression and cell signaling related to cancer cell growth (e.g., transforming growth factor beta activated kinase-1 (TAK1) signaling) in recipient HCC cells. The gene discussed is MAP3K7; the disease is hepatocellular carcinoma.