Moreover, when the sub-group of GDM treated by insulin was assessed separately, pre-gestational BMI and UA levels both during pregnancy and postpartum were higher (p = 0.039, p = 0.041, and p = 0.049, respectively, Mann–Whitney) in the sub-group requiring insulin to maintain optimal glucose levels compared to GDM women on diet only. This evidence concerns the gene INS and gestational diabetes.