FCGR2B and neoplasm: Though effector functions of galactosylated or biantennary α-2,6 sialylated IgG have been reported [37,38,39], the association between IgG1-G0F and tumor-associated macrophages may attribute to not only potent stimuli upon interactions between agalactosylated IgG-Fc and activating FcγRs, probably FcγRIII [11], but also a lack of blocking signals triggered by the binding of galactosyl/sialyl IgG to the inhibitory FcγRIIB [12].