Here, the mean levels of Se and SELENOP (86.1 μg/L in 30 sera and 5.1 mg/L in 56 sera, respectively) were slightly higher, as compared to eight other Western European countries in a prospective study, showing an association of higher levels with a decreased CRC risk (85.6 μg/L and 4.4 mg/L, respectively for the controls [7]). This evidence concerns the gene SELENOP and colorectal carcinoma.