Serum S100B increases in patients with minor head injury who do not need further neuroradiological evaluation, as studies comparing CT scans and S100B levels have demonstrated, with values below 0.12 ng/ml associated with low risk of obvious neuroradiological changes (such as intracranial hemorrhage or brain swelling) or significant clinical sequelae (Wolf, Ruzicka, & Yuspa, 2010). The gene discussed is S100B; the disease is intracranial hemorrhage.