Genetic profile of ADIPOQ (c.G276T, rs1501299), KCNJ11 (g.5635A>G, rs5219) and TCF7L2 (g.53341C>T, rs7903146) genes in Kyrgyz population, as well as the association with T2D have never been studied before. The gene discussed is KCNJ11; the disease is type 2 diabetes mellitus.