TCF7L2 and type 2 diabetes mellitus: Genetic predisposition to T2D was studied widely during the last decades.2, 3, 4 At present, around 50 candidate genes are considered to increase the likelihood of T2D, of which adiponectin gene (ADIPOQ), potassium channel, inwardly rectifying subfamily J, member 11 (KCNJ11) and transcription factor 7‐like 2 (TCF7L2 [IVS3C>T]) may be associated with insulin resistance and β‐cells dysfunction.5, 6, 7, 8, 9, 10, 11, 12, 13 Carriage of various SNP combinations may explain clinical heterogeneity of this disease.