For instance, overexpression of let‐7a suppressed PTC cell migration and tumour growth by targeting AKT2.42 Exogenous IGF‐2 expression, a potent stimulus facilitated cancer progression, could reversed NEAT1‐knockdown‐induced growth inhibition, might be a direct target of let‐7a.43 Thus, overexpression of let‐7a suppressed cell migration and angiogenesis, which also supported our study that shown in Figure 2. This evidence concerns the gene AKT2 and cancer.