This is in contrast to AD where we confirm previous findings of significantly increased apoD protein levels [C vs AD–SFC; p = 0.005, ITC; p = 0.002] (Belloir et al. 2001; Glockner and Ohm 2003; Desai et al. 2005; Bhatia et al. 2013) (Fig. 1a, b). This evidence concerns the gene APOD and Alzheimer disease.