LMNB1 and hepatocellular carcinoma: With regards to plasma levels of lamin B1 (2-ΔΔCq), there was a significant increase in patients with stages A and B HCC compared to patients with stage 0 disease, with a median (Q1–Q3) in stage 0, A and B of 2.0 (1.7–2.4), 5.1 (3.7–6) and 19.1 (14.7–28.2), respectively.