It has been found that BALR are able to predict the cytogenetic subtypes of B-acute lymphoblastic leukemia (B-ALL) among the most prevalent abnormalities: mixed lineage leukemia (MLL) rearrangement, E2A-PBX1 translocation, and TEL-AML1 fusion. This evidence concerns the gene RUNX1 and precursor B-cell acute lymphoblastic leukemia.