As a newly discovered tumor suppressor, PAQR3 is a protein that modulates various cellular functions (Feng et al., 2007, Hewavitharana and Wedegaertner, 2015, Jiang et al., 2010, Liu et al., 2015, Wang et al., 2013, Wang et al., 2017, Xu et al., 2015, Xu et al., 2016). Here, PAQR3 is linked to neoplasm.