To surmise the role of GINS complex in the reactivation of quiescent stem-like glioma cells lying dormant in the peri-necrotic niche, the expression of GINS components, PSF1, PSF2, PSF3 and SLD5, in human glioblastoma tissues was analyzed by immunohistochemistry. This evidence concerns the gene GINS4 and central nervous system cancer.