APOH and systemic lupus erythematosus: The aPL, namely lupus anticoagulant (LA), anticardiolipin antibody (aCL), or anti-β2 glycoprotein-I antibody (anti-β2GpI) are usually found in the primary antiphospholipid syndrome (APS), but can be associated with other connective tissue diseases (mainly systemic lupus erythematosus), infections, drugs, and malignancies.