Statistical analysis revealed that KC, IL-6 as well as MCP-1 levels were increased in the plasma of saline-infused CSC [MWU test: KC: P = 0.016 (Figure 4A); IL-6: P = 0.004 (Figure 4B); MCP-1: P = 0.028 (Figure 4C)] and CSC-recipient CSC (MWU test: KC: P = 0.008; IL-6: P = 0.048; MCP-1: P = 0.004) vs. respective SHC animals. The gene discussed is CALCA; the disease is keratoconus.