Recently, additional small molecule splicing inhibitors were identified, such as caffeine, digoxin, amiloride, sudemycins et al. In cervical cancer cells, caffeine and digoxin could reduce expression of the serine/arginine-rich splicing factor 3 (SRSF3) and increase expression of a p53b isoform. Here, SRSF3 is linked to cervical carcinoma.