All tested GBM cell lines were highly positive for the agonistic receptor DR5, implying a possible responsiveness to TRAIL apoptotic effect and did not express DcR1 and DcR2, exception made for U87MG where intermediate levels of DcR2 were detected, as previously described by Röhn et al. [31]. This evidence concerns the gene TNFRSF10C and glioblastoma.