We found that enforced expression of FOXM1 renders myeloma partially resistant to both drugs, as evidenced by half-maximal inhibitory concentrations (IC50) that, in case of Bz, were 5.6-fold (CAG) and 1.9-fold (XG1) higher in FOXM1Hi than FOXM1N cells (Fig. 3a, left). This evidence concerns the gene FOXM1 and plasma cell myeloma.