In regard to diverse biological functions attributable to FOXM1 in myeloma, the transcription factor seems to resemble well-established “master” transcription factors of myeloma, such as interferon regulatory factor 4 or IRF4 (a.k.a. MUM1) [28] and the myelocytomatosis oncoprotein MYC [29]. Here, IRF4 is linked to plasma cell myeloma.