Focal adhesions of mesenchymal cells generated through EMT are hubs of molecular reactions, such as the TGFβ-induced mobilization of the adaptor protein lipoma preferred partner (LPP) to focal adhesions, which crosslinks actin microfilaments to α-actinin and integrin complexes in order to facilitate breast cancer cell motility [54]. The gene discussed is TGFB1; the disease is breast cancer.