SLC29A1 and metastatic neoplasm: The knock-out mice showed similar results as the EMT reporter mice, as pancreatic cancer did not show signs of EMT in the metastatic tumors; however, the EMT suppressed the expression of drug transporters, including the equilibrative nucleoside transporter 1 (ENT1) and the concentrating nucleoside transporter 3 (Cnt3), which assisted the metastatic tumor cells to escape from the injection of anti-cancer drugs used to treat the mice [133].