Likewise, the myxoma viral protein Serp1 is an anti-inflammatory inhibitor of serine proteases; administration of Serp1 causes a non-neutralizing antibody response and subsequently the functional activity of the protein has been extended (and potential immunogenicity decreased) through development of small peptide mimetics that replicate the function of the full protein (Ambadapadi et al., 2016). The gene discussed is SERP1; the disease is myxoma.