Compared to women with less aggressive BC, as assessed by a Ki67<29%, those with more aggressive BC (Ki67>28%) did not show differences in the AHI (median 5.0, IQR 1.5–10, vs 5.1, IQR 2.6–8.3, p = 0.89), or ODI4 (median 1.4, IQR 0.3–5.4 vs 1.9, IQR 0.5–5.8, p = 0.57) (Fig 2). The gene discussed is MKI67; the disease is breast cancer.