An exome-wide association study has also identified a number of missense SNPs in RTEL1, including rs3208008 (Q1042H) and rs115303435 (A1059T), in a Han Chinese population, although rs115303435 showed marginal association with GBM risk after conditional analysis by rs6010620 (P = .059) [25]. Here, RTEL1 is linked to glioblastoma.