RAMP1 and Hepatitis: Considering the different mortality rates and mechanisms of liver injury between the two genotypes, it may be that Ly6Chigh/CD11bhigh/F4/80high monocyte-derived macrophages in WT mice contribute to resolution of inflammation after ConA hepatitis, while Ly6Chigh/CD11bhigh/F4/80low monocyte-derived macrophages in Ramp1-/- mice exacerbate inflammation in response to ConA.