Furthermore, chemokines such as Growth-Regulated Oncogene-alpha (Groα or CXCL1), growth-Regulated Oncogene-beta (Groβ) and monocyte chemoattractant protein 1 (MCP-1) have demonstrated an important role in the regulation of local immunity against infections by contributing to the tissue infiltration of leukocytes [10]. The gene discussed is CXCL1; the disease is infection.