Besides, physiological PCT can increase from 1 to 10 ng/mL in normal neonates within 48 hours after delivery.[35,36] IL-6 is a pleiotropic cytokine that is expressed by different cells in response to infections.[22] Furthermore, IL-6 can be detected rapidly by flow cytometry with minimal blood volumes (0.05 mL). This evidence concerns the gene IL6 and infection.