In Yersinia, especially the RNases PNPase and RNase E were found to occupy well-established roles in the regulation of virulence factors and growth under several infection-relevant conditions (oxidative and cold stress) (Rosenzweig et al., 2007; Yang et al., 2008; Rosenzweig and Chopra, 2013). Here, PNPT1 is linked to infection.