ITGAM and mesothelioma: Similar to previous studies, the proportion of macrophages (CD11b+F4/80+Ly6G-Siglec-F-) in the BM and spleen increased during healthy aging, however, this did not further increase during mesothelioma tumor growth (Wang et al., 1995; Jackaman et al., 2013; (Supplementary Figure S3).