Component of theIL-17R complex with IL-17RA; mediates the functions of both IL-17A and IL-17F proinflammatory cytokines; involved in host defense, innate immunity, tissue remodeling, and acute phase responses; implicated in the progression of inflammatory and autoimmune diseases; enhances IFNg secretion by NK cells. This evidence concerns the gene IL17RA and autoimmune disease.