As shown in Figure 5, AT-101 reduced the expression of ErbB2 in all MM cell lines (MM-F1, p = 0.004; MM-B1, p = 0.002; H-Meso-1, p = 0.003; #40a, p = 0.0003) as compared to DMSO-treated cells. This evidence concerns the gene ERBB2 and Miyoshi myopathy.