Roles of TGaseII (Eom et al., 2014a), SOCS1 (Noh et al., 2017), COX-2 (Kwon et al., 2015), and HDAC3 (Kim et al., 2012; Eom et al., 2014b) in allergic inflammation, such as anaphylaxis, have been previously reported. The gene discussed is HDAC3; the disease is anaphylaxis.