Some studies have reported polymorphisms in IL-1α, IL-1β, and IL-1Ra in subjects who develop epilepsy as adults (Kanemoto et al., 2000; Haspolat et al., 2005; Nakayama and Arinami, 2006; Serdaroglu et al., 2009; Chou et al., 2010). The gene discussed is IL1A; the disease is epilepsy.