To determine the effect of SKA3 on CC tumor growth in vivo, xenograft mouse models were established by injecting HeLa cells with stable SKA3 overexpression into the left dorsal flank, cells with stable SKA3 knockdown into the right dorsal flank, and cells stably expressing the control plasmid into the middle dorsal flank of different animals. Here, SKA3 is linked to neoplasm.