TMPRSS2 and posterior cortical atrophy: In Fig. 2a, d, we found that TMPRSS2-ERG fusion was more common in the T3–4 stages of PCa than in the T1–2 after excluding the two studies with heterogeneity Petterson et al. [19] and Zhou et al. [20] (P < 0.01), and the pooled OR and 95% CI was 1.40 (1.33–1.48).