CHST14 and Ehlers-Danlos syndrome: (2) The loss of dermatan sulfate (a glycosaminoglycan species related to CS), due to lack of the enzymes such as galactosyltransferase 1 (B4GalT7), galactosyltransferase II (B3GALT6), or CHST14/dermatan 4-O-sulfotransferase-1 (D4ST1), are reported to cause EDS-like connective tissue disorder48,50.