VEGFA and neoplasm: Our study revealed 1) a suggestive association between high baseline/pre-treatment microvascular rCBF and panvascular rCBV and rCBF within the edema ROI and an increased risk of disease progression; 2) a statistically significant association between high week 5 and pre-C1 Ktrans values in the tumor ROI and worse PFS; and 3) a statistically significant association between high week 6 VEGF levels and worse OS.