CDH23 and hearing loss disorder: These findings are in agreement with ours and other authors observations that different diseases can be caused by the same gene depending on specific mutations, such as USH2A that can cause either nsRP or USH, or the USH genes MYO7A, USH1C, CDH23, PCDH15, USH1G, WHRN or CIB2 that can cause non syndromic hearing loss or USH41–48.