MYH14 and carcinoma: Here we observed that for carcinoma cells without robust myosin motor activity, dendritic protrusions require MTs (±nocodazole treatment) on quasi-2D surfaces but not in response to biaxial cues where they are dispensable during development of guided dendritic protrusions, as well as dendritic-directed migration (Supplementary Figure 4a, Supplementary Movie 7).