(a-b) Splenic weights depicted as percentage of initial body weights for NST-LNP controls (n = 7), and IL-12-LNP-treated (n = 7) healthy mice (a); and for NST-LNP controls (n = 7), and IL-12-LNP-treated (n = 7) MYC-driven HCC mice (b). The gene discussed is MYC; the disease is hepatocellular carcinoma.