In IgAN/HSP median number of dendrin positive nuclei was 1.67 (min - max: 0.00–5.60) and in podocytopathies 3.90 (min – max: 0.00–23.10), (P = 0.028, Z = 2.2, r = 0.38, 95% CI 0.12–4.34). This evidence concerns the gene DDN and hereditary spastic paraplegia.