CEACAM5 and neoplasm: The ability of discrimination of the CEA clearance pattern, as assessed by AUC, was 0.64 (95% CI, 0.51–0.77), 0.66 (95% CI, 0.53–0.79), and 0.69 (95% CI, 0.52–0.85) for TRG, tumor downstaging, and pCR (Fig. 3), respectively.