In a retrospective analysis, patients with increased tumor-infiltrating CD8+ lymphocytes (TILs) within advanced UC (pT2, pT3 or pT4) have better disease-free survival and OS than patients with similar-staged UC and fewer intratumoral CD8 TILs, suggesting that intratumoral TIL infiltration is associated with better outcome [14]. Here, CD8A is linked to neoplasm.