CD4 and tuberculosis: Studies focusing on TB mortality within the first 3 months are scarce; in the majority of these published studies, the population studied were hospitalised patients.10 In 2008, Botswana introduced guidelines for CPT and ART for TB and HIV co-infected patients regardless of their CD4 levels11; this was even before the global 2010 recommendation.9,10 After implementing such measures, it is crucial to evaluate how Mahalapye Health District (MHD) performed and how far the district is in attaining the 2025 WHO TB mortality target.