Evaluation of 39 cases of sporadic or familial pheochromocytoma/paraganglioma and pituitary adenomas for abnormalities in known pheochromocytoma/paraganglioma susceptibility genes (SDHx, SDHAF2, RET, VHL, TMEM127, MAX, and FH) and known pituitary adenoma genes (MEN1, AIP, and CDKN1B) demonstrated 11 germline mutations (SDHB, SDHC, and SDHAF2) and four variants of unknown significance (SDHA, SDHB, and SDHAF2) [101]. The gene discussed is SDHB; the disease is pituitary gland adenoma.