In all subjects, BMI, WHR, trunk fat, ALT, fasting glucose, HOMA-IR, TG, HDL-C, cholesterol, LDL-C and UA were all chosen as independent variables before and after adjusting for age, sex, current smoking and drinking, physical activity, hypertension, diabetes (except for cholesterol and LDL-C, all p <  0.001). The gene discussed is GPT; the disease is Hypertension.