SRSF3 and acute myeloid leukemia: Given its affects on cell physiology it is not surprising that SRSF3 protein expression is elevated in a variety of cancers (Jia et al., 2010), while its mRNA levels are downregulated in de novo diagnosed AML patients (Liu et al., 2012) suggesting that SRSF3 levels could be crucial for maintaining normal cellular homeostasis in that context.