EoE+FI patients present with significantly lower transcript counts of CPA3, a mast cell specific transcript that encodes for carboxypeptidase a3, as well as lower FCER1B, the mast cell and basophil specific beta chain of the high-affinity IgE receptor (Figures 4B,C). The gene discussed is CPA3; the disease is eosinophilic esophagitis.