Moreover, with the Solitaire With the Intention For Thrombectomy Plus Intravenous t-PA Versus DIRECT Solitaire Stent-retriever Thrombectomy in Acute Anterior Circulation Stroke (SWIFT DIRECT) trial actively recruiting (www.ClinicalTrials.gov NCT03192332), a randomized controlled trial will hopefully help to define the current role of IV thrombolysis in stroke treatment. This evidence concerns the gene PLAT and Stroke.