IL18 and Alzheimer disease: Our result complements a whole body of literature describing that IL-18 might inhibit the cellular mechanisms underlying learning and memory (Curran and O’Connor, 2001) and participate in different ways to neuronal damage (Alboni et al., 2010), proposing that this pro-inflammatory cytokine and its related molecular pathways are of some relevance in AD pathogenesis (Bossù et al., 2010).