P7C3 obviously decreases the tyrosine hydroxylase (TH) neuronal loss in the SNpc and striatum in MPTP (De Jesús-Cortés et al., 2012; Gu et al., 2017) mouse or 6-hydroxydopamine (6-OHDA; De Jesús-Cortés et al., 2015) rat model of PD. This evidence concerns the gene TH and Parkinson disease.