Since abnormal migration of adult-born hippocampal neurons was also described in schizophrenia (Duan et al., 2007; Kim et al., 2009), and rare inherited copy number variants of RAPGEF2 have been associated with familiar schizophrenia (Xu et al., 2009), Han et al. (2016) went on to study the role of miR-19 and RAPGEF2 in schizophrenia patient-derived hippocampal neural progenitor cells (SZ-NPCs). This evidence concerns the gene RAPGEF2 and schizophrenia.