Sca-1+CD24+ cells formed organoids at a higher rate than other primary tumor populations (5.8 vs. 3.1, 3.3, and 1.9%, P = 0.002, P = 0.0007, P = 0.0002, t test), demonstrating that more efficient in vitro organoid formation correlates with a TPC-enriched population (Supplementary Fig. 1c). Here, CD24 is linked to neoplasm.